Should be a document about optimisation of rAAV production based on transcriptomics for optimisation and to identify best cell lines and settings of the production at different scales This is a project that was done to show to client what they should bexpecting in terms of resukts
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As a healthcare professional with a background in laboratory technology, this study focuses on the use of transcriptomic analyses to identify targets for enhancing adeno-associated virus (AAV) production. The methods include RNA-sequencing, clonal cell line generation, AAV harvest, and purification. The results highlight differentially expressed pathways associated with improved AAV production and the use of pharmacological modulation to enhance production. The study concludes with a summary...